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max in WT synaptoneurosomes, suggesting that Src signaling may be downregulated in KI synapses. Conversely, our power to rescue SERT function in KI midbrain synaptoneurosomes by the inhibition of FAK implies elevated FAK signaling downstream of the Pro32Pro33 mutant, as verified by greater pFAK localization in five-HT synapses. Our knowledge thus a